Promethazine HCl Oral Solution may possibly reduced seizure threshold. It should be employed with caution in individuals with seizure Ailments or in people that are employing concomitant prescription drugs, for instance narcotics or area anesthetics, which can also affect seizure threshold.
It's important that Promethazine HCl Oral Alternative is measured with the exact measuring device (see Safeguards-Details for Patients). A residence teaspoon is not an accurate measuring system and may lead to overdosage, specially when half a teaspoon should be to be measured.
Promethazine is usually a phenothiazine spinoff which differs structurally from your antipsychotic phenothiazines by the presence of a branched aspect chain and no ring substitution.
Pregnancy Tests: Diagnostic pregnancy exams dependant on immunological reactions amongst HCG and anti-HCG may cause Phony-damaging or Phony-optimistic interpretations.
Promethazine HCl Oral Remedy should be utilized with caution in patients with bone-marrow depression. Leukopenia and agranulocytosis happen to be noted, generally when Promethazine (Promethazine HCl) is used in association with other known marrow-harmful brokers.
Codeine could boost the neuromuscular blocking motion of skeletal muscle relaxants and create an increased degree of respiratory depression.
Sedation This products relieves apprehension and induces a tranquil rest from which the affected person can be easily aroused.
Lower blood pressure. A sudden fall in blood pressure can transpire in many people all through remedy with Promethazine Hydrochloride and Codeine Phosphate Oral Solution and this may well trigger you to sense dizzy, faint, lightheaded, or weak, especially when you get up (orthostatic hypotension). Your possibility of getting this problem might be greater if you are taking Promethazine Hydrochloride and Codeine Phosphate Oral Answer with specified other medicines that lessen blood pressure.
Right after initiation of therapy in little ones or Older people, dosage should be altered to the smallest amount sufficient to relieve signs. The administration of Promethazine HCl in 25-mg doses will Handle slight transfusion reactions of an allergic nature.
It's hard to ascertain read more what constitutes a regular harmful or lethal dose. Nonetheless, the lethal oral dose of codeine in an Grownup is noted for being while in the range of 0.
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Call nearby state Specialist licensing board or state controlled substances authority for info on how to forestall and detect abuse or diversion of the merchandise.
Promethazine HCl Oral Solution needs to be utilised through pregnancy provided that the probable profit justifies the opportunity risk towards the fetus.
Sedating medicines may well trigger confusion and in excess of-sedation during the aged; elderly individuals normally need to be began on minimal doses of Promethazine HCl Oral Option and noticed intently.